Opipramol dihydrochloride

Amorphous

Therapeutic Area

Nervous system

Status

Commercial

EU DMF readiness

CAS No.

909-39-7

Reference Product

Insidon/NOVARTIS

Drug description:

Opipramol hydrochloride acts as an anxiolytic and antidepressant agent.
Opipram is indicated for the treatment of generalized anxiety disorder (GAD) and somatoform disturbances.
It is formulated as film-coated tablets for oral route of administration.

Mechanism of action:

Opipramol is a tricyclic antidepressive agent. Opipramol acts as a high affinity sigma receptor agonist, primarily of the σ1 subtype, but also of the σ2 subtype with lower affinity. Cyclic antidepressants block the absorption of the neurotransmitters serotonin and norepinephrine, making more of these chemicals available in the brain.