Ticagrelor

Form II

Therapeutic Area

Blood & blood forming organs

Status

Pipeline

EU DMF readiness

US DMF readiness

CEP

Other documentation

Canadian DMF
Brazilian DMF

CAS No.

274693-27-5

Reference Product

BRILINTA, BRILIQUE/AstraZeneca

Drug description:

Ticagrelor is an antiplatelet agent.
Ticagrelor co-administered with acetylsalicylic acid (ASA), is indicated for the prevention of atherothrombotic events in adult patients with acute coronary syndromes (ACS) or a history of myocardial infarction (MI) and a high risk of developing an atherothrombotic event.
It is formulated as tablets, film-coated tablets for oral route of administration.

Mechanism of action:

Ticagrelor is a platelet ADP P2Y12 receptor antagonist. It helps to prevent the formation of blood clots and reduces the occurrence of thrombotic events in acute coronary syndromes (ACS). ADP mediates platelet aggregation through its action on two G-protein-coupled receptor subtypes. The drug candidate is also acts by preventing adenosine from being cleared from the blood stream and by marginally increasing the levels of immune cell activity.